"Me So Horny" is 2 Live Crew's most successful single, and the leading single from "As Nasty As They Wanna Be".

The song hip hop beat is sampled from Mass Production's "Firecracker" song, and the hook is sampled from Stanley Kubrick's film Vietnam War move "Full Metal Jacket" (click to watch the original scene.

The song reached #26 a the Billboard's Hot 100 singles chart and #1 at the Billboard Hot Rap. The single had been a massive blockbuster in stores but didn't gained much radio plays due to the explicit dirty lyrics.

The song charted #83 at the VH1 100 Greatest Songs in Hip Hop for 2008.